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1

Competition in a technological niche: the cars of the future

Bakker, Sjoerd, van Lente, Harro, Engels, Remko

Journal:

Technology Analysis & Strategic Management

Year:

2012

Language:

english

File:

PDF, 347 KB

english, 2012

2

The histamine H3 receptor: from gene cloning to H3 receptor drugs

Leurs, Rob, Bakker, Remko A., Timmerman, Henk, de Esch, Iwan J. P.

Journal:

Nature Reviews Drug Discovery

Year:

2005

Language:

english

File:

PDF, 317 KB

english, 2005

3

Pharmacogenomic and Structural Analysis of Constitutive G Protein–Coupled Receptor Activity

Smit, Martine J., Vischer, Henry F., Bakker, Remko A., Jongejan, Aldo, Timmerman, Henk, Pardo, Leonardo, Leurs, Rob

Journal:

Annual Review of Pharmacology

Year:

2007

Language:

english

File:

PDF, 609 KB

english, 2007

4

Facilities for monitoring blood flow during MR-guided diagnostic and therapeutic interventions

Chris J.G. Bakker, Remko van der Weide, Henk F.M. Smits

Journal:

Journal of Magnetic Resonance Imaging

Year:

1999

Language:

english

File:

PDF, 241 KB

english, 1999

5

Placement of an inferior vena cava filter in a pig guided by high-resolution MR fluoroscopy at 1.5 T

Lambertus W. Bartels, Clemens Bos, Remko van der Weide, Henk F.M. Smits, Chris J.G. Bakker, Max A. Viergever

Journal:

Journal of Magnetic Resonance Imaging

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

6

On-line flow quantification by low-resolution phase-contrast MR imaging and model-based postprocessing

Remko van der Weide, Chris J.G. Bakker, Romhild M. Hoogeveen, Max A. Viergever

Journal:

Journal of Magnetic Resonance Imaging

Year:

2000

Language:

english

File:

PDF, 236 KB

english, 2000

7

MR-guided balloon angioplasty: In vitro demonstration of the potential of MRI for guiding, monitoring, and evaluating endovascular interventions

Chris J. Bakker, Henk F. Smits, Clemens Bos, Remko van der Weide, Karel J. Zuiderveld, Joop J. van Vaals, Wenzel F. Hurtak, Max A. Viergever, Willem P. Mali

Journal:

Journal of Magnetic Resonance Imaging

Year:

1998

Language:

english

File:

PDF, 973 KB

english, 1998

8

Adaptive subtraction as an aid in MR-guided placement of catheters and guidewires

Chris J.G. Bakker, Jan-Henry Seppenwoolde, Lambertus W. Bartels, Remko van der Weide

Journal:

Journal of Magnetic Resonance Imaging

Year:

2004

Language:

english

File:

PDF, 479 KB

english, 2004

9

Fully MR-guided hepatic artery catheterization for selective drug delivery: A feasibility study in pigs

Jan-Henry Seppenwoolde, Lambertus W. Bartels, Remko van der Weide, Johannes F.W. Nijsen, Alfred D. van het Schip, Chris J.G. Bakker

Journal:

Journal of Magnetic Resonance Imaging

Year:

2006

Language:

english

File:

PDF, 479 KB

english, 2006

10

Resolution-insensitive velocity and flow rate measurement in low-background phase-contrast MRA

Remko van der Weide, Max A. Viergever, Chris J. G. Bakker

Journal:

Magnetic Resonance in Medicine

Year:

2004

Language:

english

File:

PDF, 251 KB

english, 2004

11

New high affinity H3 receptor agonists without a basic side chain

Ruengwit Kitbunnadaj, Marcel Hoffmann, Silvina A. Fratantoni, Gerold Bongers, Remko A. Bakker, Kerstin Wieland, Ahmed el Jilali, Iwan J.P. De Esch, Wiro M.P.B. Menge, Henk Timmerman, Rob Leurs

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 281 KB

english, 2005

12

Synthesis and structure–activity relationships of indole and benzimidazole piperazines as histamine H4 receptor antagonists

Nalan Terzioglu, Richard M. van Rijn, Remko A. Bakker, Iwan J.P. De Esch, Rob Leurs

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 303 KB

english, 2004

13

Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor

Venkata R. P. Ratnala, Herman G. P. Swarts, Jenny VanOostrum, Rob Leurs, Huub J. M. DeGroot, Remko A. Bakker, Willem J. DeGrip

Journal:

Year:

2004

Language:

english

File:

PDF, 271 KB

english, 2004

14

The Akt/GSK-3β axis as a new signaling pathway of the histamine H3 receptor

Gerold Bongers, Tina Sallmen, Maria Beatrice Passani, Chiara Mariottini, Dominique Wendelin, Adrian Lozada, André van Marle, Marjon Navis, Patrizio Blandina, Remko A. Bakker, Pertti Panula, Rob Leurs

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 476 KB

english, 2007

15

Pharmacological characterization of the new histamine H4 receptor agonist VUF 8430

Herman D Lim, Maristella Adami, Elena Guaita, Thomas Werfel, Rogier A Smits, Iwan JP De Esch, Remko A Bakker, Ralf Gutzmer, Gabriella Coruzzi, Rob Leurs

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 759 KB

english, 2009

16

Linking agonist binding to histamine H1 receptor activation

Jongejan, Aldo, Bruysters, Martijn, Ballesteros, Juan A, Haaksma, Eric, Bakker, Remko A, Pardo, Leonardo, Leurs, Rob

Journal:

Nature Chemical Biology

Year:

2005

Language:

english

File:

PDF, 434 KB

english, 2005

17

Molecular aspects of the histamine H3 receptor

Gerold Bongers, Remko A. Bakker, Rob Leurs

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.61 MB

english, 2007

18

Mutational analysis of the histamine H1-receptor binding pocket of histaprodifens

Martijn Bruysters, Heinz H Pertz, Aloys Teunissen, Remko A Bakker, Michel Gillard, Pierre Chatelain, Walter Schunack, Henk Timmerman, Rob Leurs

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 289 KB

english, 2004

19

A framework for performance and data quality assessment of Radio Frequency IDentification (RFID) systems in health care settings

Remko van der Togt, Piet. J.M. Bakker, Monique W.M. Jaspers

Journal:

Journal of Biomedical Informatics

Year:

2011

Language:

english

File:

PDF, 786 KB

english, 2011

20

Constitutive activity of the histamine H1 receptor reveals inverse agonism of histamine H1 receptor antagonists

Remko A Bakker, Kerstin Wieland, Henk Timmerman, Rob Leurs

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 75 KB

english, 2000

21

Constitutive activity of G protein coupled receptors and drug action

Rob Leurs, Maria Sol Rodriguez Pena, Remko A Bakker, Astrid E Alewijnse, Henk Timmerman

Journal:

Pharmaceutica Acta Helvetiae

Year:

2000

Language:

english

File:

PDF, 153 KB

english, 2000

22

GPCR Proteomics: Mass Spectrometric and Functional Analysis of Histamine H 1 Receptor after Baculovirus-Driven and in Vitro Cell Free Expression

Sansuk, Kamonchanok, Balog, Crina I. A., van der Does, Anne M., Booth, Raymond, de Grip, Willem J., Deelder, André M., Bakker, Remko A., Leurs, Rob, Hensbergen, Paul J.

Journal:

Journal of Proteome Research

Year:

2008

Language:

english

File:

PDF, 970 KB

english, 2008

23

Sampling and quantifying invertebrates from drinking water distribution mains

J.Hein M. van Lieverloo, Dick W. Bosboom, Geo L. Bakker, Anke J. Brouwer, Remko Voogt, Josje E.M. De Roos

Journal:

Year:

2004

Language:

english

File:

PDF, 267 KB

english, 2004

24

Modulation of constitutive GPCR activity: a way of life?

Rob Leurs, Remko A. Bakker, Paola Casarosa, Dennis Verzijl, Henk Timmerman, Martine J. Smit

Journal:

International Congress Series

Year:

2003

Language:

english

File:

PDF, 86 KB

english, 2003

25

Characterization of the Histamine H 4 Receptor Binding Site. Part 1. Synthesis and Pharmacological Evaluation of Dibenzodiazepine Derivatives

Smits, Rogier A., Lim, Herman D., Stegink, Bart, Bakker, Remko A., de Esch, Iwan J. P., Leurs, Rob

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 183 KB

english, 2006

26

Discovery of S -(2-Guanidylethyl)-isothiourea (VUF 8430) as a Potent Nonimidazole Histamine H 4 Receptor Agonist

Lim, Herman D., Smits, Rogier A., Bakker, Remko A., van Dam, Cindy M. E., de Esch, Iwan J. P., Leurs, Rob

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 44 KB

english, 2006

27

Identification of 4-(1 H -Imidazol-4(5)-ylmethyl)pyridine (Immethridine) as a Novel, Potent, and Highly Selective Histamine H 3 Receptor Agonist

Kitbunnadaj, Ruengwit, Zuiderveld, Obbe P., Christophe, Bernard, Hulscher, Saskia, Menge, Wiro M. P. B., Gelens, Edith, Snip, Erwin, Bakker, Remko A., Celanire, Sylvain, Gillard, Michel, Talaga, Patri

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 63 KB

english, 2004

28

Brain correlates of auditory hallucinations: Stimulus detection is a potential confounder

van Lutterveld, Remko, Diederen, Kelly, Schutte, Maya, Bakker, Romy, Zandbelt, Bram, Sommer, Iris

Journal:

Schizophrenia Research

Year:

2013

Language:

english

File:

PDF, 347 KB

english, 2013

29

Hemodialysis Access Flow Phantom

Smits, Henk F.M., Bos, Clemens, van der Weide, Remko, Bakker, Chris J.G.

Journal:

Journal of Vascular and Interventional Radiology

Year:

1998

Language:

english

File:

PDF, 10.88 MB

english, 1998

30

Synthesis and Structure−Activity Relationships of Conformationally Constrained Histamine H 3 Receptor Agonists

Kitbunnadaj, Ruengwit, Zuiderveld, Obbe P., De Esch, Iwan J. P., Vollinga, Roeland C., Bakker, Remko, Lutz, Martin, Spek, Anthony L., Cavoy, Emile, Deltent, Marie-France, Menge, Wiro M. P. B., Timmerm

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 212 KB

english, 2003

31

A Chemical Switch for the Modulation of the Functional Activity of Higher Homologues of Histamine on the Human Histamine H 3 Receptor: Effect of Various Substitutions at the Primary Amino Function

Govoni, Marinella, Lim, Herman D., El-Atmioui, Dris, Menge, Wiro M. P. B., Timmerman, Henk, Bakker, Remko A., Leurs, Rob, De Esch, Iwan J. P.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 132 KB

english, 2006

32

Synthesis and Pharmacological Identification of Neutral Histamine H 1 -Receptor Antagonists

Govoni, Marinella, Bakker, Remko A., van de Wetering, Ineke, Smit, Martine J., Menge, Wiro M. B. P., Timmerman, Henk, Elz, Sigurd, Schunack, Walter, Leurs, Rob

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 183 KB

english, 2003

33

Histamine H3 receptor ligands with a 3-cyclobutoxy motif: a novel and versatile constraint of the classical 3-propoxy linker

Wijtmans, Maikel, Denonne, Frédéric, Célanire, Sylvain, Gillard, Michel, Hulscher, Saskia, Delaunoy, Christel, Van houtvin, Nathalie, Bakker, Remko A., Defays, Sabine, Gérard, Julien, Grooters, Luc, H

Journal:

Year:

2010

Language:

english

File:

PDF, 193 KB

english, 2010

34

Rapid Detection of theDPYDIVS14+1G>A Mutation for Screening Patients to Prevent Fluorouracil-Related Toxicity

Dr Tessa M. Bosch,Remko Bakker,Jan H. M. Schellens…

Journal:

Molecular Diagnosis & Therapy

Year:

2007

Language:

english

File:

PDF, 98 KB

english, 2007

35

N -Substituted Piperidinyl Alkyl Imidazoles: Discovery of Methimepip as a Potent and Selective Histamine H 3 Receptor Agonist

Kitbunnadaj, Ruengwit, Hashimoto, Takeshi, Poli, Enzo, Zuiderveld, Obbe P., Menozzi, Alessandro, Hidaka, Ryoko, de Esch, Iwan J. P., Bakker, Remko A., Menge, Wiro M. P. B., Yamatodani, Atsushi, Coruzz

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

36

Functional CD47/signal regulatory protein alpha (SIRPα) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo

Nicolas Legrand, Nicholas D. Huntington, Maho Nagasawa, Arjen Q. Bakker, Remko Schotte, Hélène Strick-Marchand, Sandra J. de Geus, Stephan M. Pouw, Martino Böhne, Arie Voordouw, Kees Weijer, James P.

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

37

Comparative Analysis of Binding Kinetics and Thermodynamics of Dipeptidyl Peptidase-4 Inhibitors and Their Relationship to Structure

Schnapp, Gisela, Klein, Thomas, Hoevels, Yvette, Bakker, Remko A., Nar, Herbert

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.64 MB

english, 2016

38

Molecular Cloning and Pharmacological Characterization of a Molluscan Octopamine Receptor

Gerhardt, Cindy C., Bakker, Remko A., Piek, Gerard J., Planta, Rudi J., Vreugdenhil, Erno, Leysen, Josée E., Van Heerikhuizen, Harm

Journal:

Molecular Pharmacology

Year:

1997

Language:

english

File:

PDF, 447 KB

english, 1997

39

Direct IR spectroscopic detection of a low-lying electronic state in a metal carbide cluster

Chernyy, Valeriy, Logemann, Remko, Kirilyuk, Andrei, Bakker, Joost M.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.04 MB

english, 2018

40

Cover Feature: Direct IR Spectroscopic Detection of a Low-Lying Electronic State in a Metal Carbide Cluster (ChemPhysChem 12/2018)

Chernyy, Valeriy, Logemann, Remko, Kirilyuk, Andrei, Bakker, Joost M.

Journal:

Year:

2018

File:

PDF, 827 KB

2018

41

A Single Second Shell Amino Acid Determines Affinity and Kinetics of Linagliptin Binding to Type 4 Dipeptidyl Peptidase and Fibroblast Activation Protein

Schnapp, Gisela, Hoevels, Yvette, Bakker, Remko, Schreiner, Patrick, Thomas, Klein, Nar, Herbert

Journal:

Year:

2020

File:

PDF, 1.31 MB

2020

42

Clinical Feasibility of a High-Resolution Thermal Monitoring Sheet for Superficial Hyperthermia in Breast Cancer Patients

Bakker, Akke, Zweije, Remko, Kok, Henny Petra, Kolff, Merel Willemijn, van den Bongard, H. J. G. Desiree, Schmidt, Manfred, van Tienhoven, Geertjan, Crezee, Hans

Journal:

Year:

2020

File:

PDF, 6.03 MB

2020

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